Higher Education Institutions and Responsible Research and Innovation (HEIRRI) foster an alignment of research and innovation (R&I) with the needs, values and societal expectations. The six key aspects of “Responsible Research and Innovation (RRI)”-societal/public engagement, gender equality, open access, science education, ethics and governance in R&I-are transdisciplinary included at all stages of formation of scientist and engineers, and other professional fields involved in R&I.